2000 Wheelersburg Football Schedule
| Aug. 25 | Ironton | Home | L 3 - 10 |
| Sep. 1 | Martins Ferry | Away | L 15 - 18 |
| Sep. 8 | Paint Valley | Away | W 48 - 14 |
| Sep. 15 | South Point | Home | W 23 - 7 |
| Sep. 22 | Minford | Home | L 14 - 24 |
| Sep. 29 | Russell | Away | L 28 - 34 |
| Oct. 6 | Waverly | Away | W 16 - 14 |
| Oct. 13 | Northwest | Home | W 43 - 14 |
| Oct. 20 | West | Away | W 45 - 24 |
| Oct. 27 | Portsmouth | Home | L 0 - 45 |
| Nov. 3 | Minford (playoff 1) | Away | L 0 - 28 |