2006 Wheelersburg Football Schedule
| Aug. 25 | Ironton | Home | L 24 - 21 |
| Sept. 1 | South Point | Away | L 21 - 14 |
| Sept. 8 | Portsmouth | Home | W 19 - 14 |
| Sept. 15 | Boyd County | Away | W 35 - 7 |
| Sept. 23 | St. Clairsville | Home | L 19 - 6 |
| Sept. 29 | Valley | Away | W 21 - 0 |
| Oct. 6 | Waverly | Away | L 34 - 14 |
| Oct. 13 | Northwest | Home | W 52 - 6 |
| Oct. 20 | Minford | Home | W 26 - 0 |
| Oct. 27 | West | Away | W 21 - 0 |